2-14 C]2-amino-3,8-dimethylimidazo[4,5-f ]quinoxaline (MeIQx) was administered orally (304 ng/kg body-weight dose based upon an average 70-kg-body-weight subject) to 5 human colon-cancer patients (58 to 84 years old), as well as to F344 rats and B 6 C 3 F 1 mice. Colon tissue was collected from the
β¦ LIBER β¦
MeIQx-DNA adduct formation in rodent and human tissues at low doses
β Scribed by Kenneth W Turteltaub; Robert J Mauthe; Karen H Dingley; John S Vogel; Christopher E Frantz; R.Colin Garner; Nancy Shen
- Book ID
- 114071253
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 574 KB
- Volume
- 376
- Category
- Article
- ISSN
- 0027-5107
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Ochratoxin A (OTA) is a mycotoxin which has been from control animals. Different adducts were most detected in foods of plant origin, in edible animal important in kidney and liver DNA and some were tissues, and in human sera, urine, and milk in many organ-specific. High levels of DNA adducts were c