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Medical Management of Levodopa-Associated Motor Complications in Patients with Parkinson’s Disease

✍ Scribed by Jankovic, Joseph; Stacy, Mark

Book ID
121389750
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2007
Tongue
English
Weight
155 KB
Volume
21
Category
Article
ISSN
1172-7047

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After several years of smooth and stable response to levodopa, many patients develop motor fluctuations manifested by "on" and "off" phases. There are various subtypes of motor fluctuations that have different underlying mechanisms and therapeutical strategies. The "wearing off" phenomenon may be ma