Mechanisms that Promote and Suppress Chromosomal Translocations in Lymphocytes
โ Scribed by Gostissa, Monica; Alt, Frederick W.; Chiarle, Roberto
- Book ID
- 118206565
- Publisher
- Annual Reviews
- Year
- 2011
- Tongue
- English
- Weight
- 845 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0732-0582
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Chromosomal aberrations have been associated with cancer development since their discovery more than a hundred years ago. Chromosomal translocations, a type of particular structural changes involving heterologous chromosomes, have made a critical impact on diagnosis, prognosis and treatment of cance
## Abstract The __NUP98__ gene has been reported to be fused with at least 15 partner genes in leukemias with 11p15 translocations. We report the results of screening of cases with cytogenetically documented rearrangements of 11p15 and the subsequent identification of involvement of __NUP98__ and i