Mechanisms of T-lymphocyte activation and cytotoxicity against human tumors induced by bispecific antibodies
β Scribed by C Renner; G Held; W Jung; U Sahin; M Pfreundschuh
- Book ID
- 112784538
- Publisher
- Springer-Verlag
- Year
- 1995
- Tongue
- English
- Weight
- 143 KB
- Volume
- 121
- Category
- Article
- ISSN
- 1432-1335
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have recently selected MAbs specific for different molecular forms of the TCR gammddelta (expressed by distinct cell subsets), able to activate TCR gamma/delta+ cells. Two of these reagents (GI and Al3) were used for the construction of bispecific MAbs in conjunction with a MAb (Mov 19) directed
## Abstract The specificity of autoβtumor cytotoxicity exerted by patients' T lymphocytes was investigated. Lymphocytes, both activated and nonβactivated, were used as effectors against freshly separated tumor cells. Activation was achieved by treatment with interferon (HuβIFNβΞ±), stimulation with