𝔖 Bobbio Scriptorium
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Mechanisms of resistance to EGFR inhibitors

✍ Scribed by Roberto Bianco; Teresa Gelardi; Vincenzo Damiano; Fortunato Ciardiello; Giampaolo Tortora

Book ID
107384273
Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
142 KB
Volume
2
Category
Article
ISSN
1776-2596

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Mechanisms of resistance to EGFR inhibit
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## Abstract Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that activates multiple signaling pathways, including phosphatidylinositol‐3‐kinase/v‐AKT murine thymoma viral oncogene homolog protein (Akt), has long been a target of novel therapies. Despite universal EGFR expression