Initiation and promotion in hepatocarcin
β
R. Schulte-Hermann
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Article
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1987
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Springer-Verlag
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English
β 263 KB
Initiation and promotion have been recognized as essential parts of the multi-stage concept of chemical carcinogenesis. In the liver, initiation by genotoxic carcinogens results in appearance of foci of phenotypically altered hepatocytes. Accelerated growth and phenotypic changes of these foci durin