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Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression

✍ Scribed by Ethan M. Shevach


Book ID
108152505
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
418 KB
Volume
30
Category
Article
ISSN
1074-7613

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## Abstract Regulatory T cells (Tregs) play an important role in maintaining immunological tolerance that is one of the main obstacles to overcome for improving antitumor immunity. Recently, the Treg has been shown to constitutively express OX40 (CD134), which is a member of the TNF‐receptor family