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Antigen-dependent suppression of alloresponses by Foxp3-induced regulatory T cells in transplantation

โœ Scribed by Michael H. Albert; Yan Liu; Claudio Anasetti; Xue-Zhong Yu


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
371 KB
Volume
35
Category
Article
ISSN
0014-2980

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## Abstract Interleukinโ€2 (ILโ€2) treatment is currently used to enhance T cellโ€mediated immune responses against tumors or in viral infections. At the same time, ILโ€2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that ILโ€2 is a