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Mechanisms of apoptosis induced by the synthetic retinoid CD437 in human non-small cell lung carcinoma cells

✍ Scribed by Sun, Shi-Yong; Yue, Ping; Wu, Gen Sheng; El-Deiry, Wafik S; Shroot, Braham; Hong, Waun K; Lotan, Reuben

Book ID: 110061987
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 269 KB
Volume: 18
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1202543

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## Background: Exposure of prostate carcinoma cell lines to retinoids, which function through the classical retinoic acid nuclear receptor, (rars) or retinoid x receptors (rxrs), results in minimal cytostatic inhibition of cell proliferation. ## Methods: Growth inhibition and various regulatory r