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Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells

✍ Scribed by Sun, Shi-Yong; Yue, Ping; Shroot, Braham; Hong, Waun K; Lotan, Reuben

Book ID: 110062191
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 403 KB
Volume: 18
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1202771

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## Abstract All‐trans‐retinoic acid (ATRA) has been shown to inhibit the growth of a number of ovarian tumor cell lines while others have been found to be resistant to retinoid suppression of growth. Interestingly, two synthetic retinoids, CD437 and 4‐HPR, inhibit the growth of both ATRA‐sensitive