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Mechanisms for methotrexate chemotherapy-induced osteopenia and increased adipogenesis in the bone marrow in rats

✍ Scribed by Michaela Scherer; Kristen Georgiou; Jo Cool; Bruce Foster; Cory Xian


Book ID
116320917
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
87 KB
Volume
43
Category
Article
ISSN
8756-3282

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✍ Masamichi Fukuoka; Tetsu Kobayashi; Takao Hayakawa πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 735 KB

This study reports changes in levels of ferritin, haemoglobin and transferrin in the bone marrow, liver and spleen as an attempt to determine the causes of testicular iron depletion. A single oral dose of di-n-butyl phthalate (DBP) to male rats caused a sloughing of the germ cells (at 6 h) prior to