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Mechanisms by which transcription can regulate somatic hypermutation

โœ Scribed by Wright, B E; Schmidt, K H; Minnick, M F

Book ID
110037566
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
120 KB
Volume
5
Category
Article
ISSN
1466-4879

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In this paper we show that the gene transcription velocity can depend exponentially on the first moments of the base pair distribution in DNA. As the major fraction of the DNA of eucaryotes consists of non-coding sequences of base pairs and these determine the statistical characteristics of the base