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Mechanisms of transcriptional regulation by Runt domain proteins

✍ Scribed by John C Wheeler; Katsuya Shigesada; J Peter Gergen; Yoshiaki Ito


Book ID
115647521
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
249 KB
Volume
11
Category
Article
ISSN
1084-9521

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## Abstract Runx proteins are essential for a number of developmental processes and are aberrantly expressed in many human cancers. Runx factors bind DNA and co‐factors to activate or repress genes crucial for bone formation, hematopoiesis, and neuronal development. Co‐activator activator (CoAA) is