✦ LIBER ✦
Non-coding DNA Can Regulate Gene Transcription by its Base Pair's Distribution
✍ Scribed by U. Sandler; A. Wyler
- Book ID
- 102613801
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 196 KB
- Volume
- 193
- Category
- Article
- ISSN
- 0022-5193
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✦ Synopsis
In this paper we show that the gene transcription velocity can depend exponentially on the first moments of the base pair distribution in DNA. As the major fraction of the DNA of eucaryotes consists of non-coding sequences of base pairs and these determine the statistical characteristics of the base pair's ordering, non-coding DNA plays an important role in the functioning of the genetic apparatus. In particular, it enables a new independent mechanism for the gradual regulation of gene expression in eucaryotes.