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Mechanism of Metal Chloride-Promoted Mukaiyama Aldol Reactions
β Scribed by Wong, Chiong Teck; Wong, Ming Wah
- Book ID
- 127301731
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 245 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
The halogen-catalyzed (I 2 , Br 2 , and Cl 2 ) Mukaiyama aldol (MA) reactions were investigated by ab initio MO calculations. The halogen-catalyzed MA reaction between a trihydrosilyl enol ether and formaldehyde favors a concerted pathway. In sharp contrast, the I 2 -catalyzed reaction between 1-phe
Abstra& A mechanistic study of the Mukaiyama aldol addition reaction employing benxaldehyde and hydtocinnamaldehyde along with a selection of Lewis acids including BF3aEt3, LiC104, Yb(OTf)3. Sn(OTfh, and Zn(OTfj2 is presented. The results of experiments conducted with doubly-labeled silyl ketene ace