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Mechanism of the Mukaiyama Aldol Reaction: The First Solid-State Characterization of a Trichlorotitanium Aldolate

✍ Scribed by Cozzi, Pier Giorgio; Floriani, Carlo; Chiesi-Villa, Angiola; Rizzoli, Corrado


Book ID
125996967
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
386 KB
Volume
13
Category
Article
ISSN
0276-7333

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Aldol reaction of trichlorotitanium enol
✍ Eiichi Nakamura; Isao Kuwajima πŸ“‚ Article πŸ“… 1983 πŸ› Elsevier Science 🌐 French βš– 257 KB

The trichlorotitanium enolates generally undergo an erythro \_\_\_\_\_ selective aldol reaction except one case which gives a threo aldol. A new form of the boat transition state has been proposed. The chair transition state (TS) hypothesis has been the central dogma in aldol chemistry. 1 Here we