The interaction of Hoechst 33258 with DNA has been examined to help clarify the mechanisms of banding. 1. In agreement with previous studies Hoechst fluorescence is enhanced to a greater degree in AT-rich compared to GC-rich DNA. 2. Hoechst causes an increase in the DNA Tm which is greater at the hi
Mechanism of chromosome banding: A phenomenological approach
โ Scribed by Manjubala S. Talekar; Subhash V. Talekar
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 661 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0020-7608
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
A quantitative expression is derived, using Fick's diffusion law, for varieties of experimentally observed band patterns in metaphase chromosomes.
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