✦ LIBER ✦

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

✍ Scribed by D.Andrew Burden; Neil Osheroff

Book ID: 114148332
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 345 KB
Volume: 1400
Category: Article
ISSN: 0167-4781
DOI: 10.1016/s0167-4781(98)00132-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mechanism of action of eukaryotic DNA to

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

✍ Yves Pommier; Philippe Pourquier; Yi Fan; Dirk Strumberg 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 621 KB

Clinical applications of anticancer drug

Clinical applications of anticancer drugs targeted to topoisomerase II

✍ Kenneth R. Hande 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 228 KB

Mechanisms of resistance to topoisomeras

Mechanisms of resistance to topoisomerase I-targeting drugs

✍ Rasheed, Zeshaan A; Rubin, Eric H 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 235 KB

Animal models for studying the action of

Animal models for studying the action of topoisomerase I targeted drugs

✍ Joyce Thompson; Clinton F. Stewart; Peter J. Houghton 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 528 KB

Catalytic Core of Human Topoisomerase II

Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism

✍ Lindsey, R. Hunter; Pendleton, MaryJean; Ashley, Rachel E.; Mercer, Susan L.; De 📂 Article 📅 2014 🏛 American Chemical Society 🌐 English ⚖ 671 KB

The screening of enzyme-targeted drugs

✍ C. L. Tsou 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 262 KB

In this article C . L. Tsou, of the Institute of Biophysics, Beijing, criticizes the use of the expression I,,, the inhibitor concentration to produce 50% inhibition of a particular enzyme as a 'most unfortunate' parameter, when screening enzyme inhibitors designed as drugs. Comments on Dr Tsou's po