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Measurement of in vivo microsomal epoxide hydrolase activity in white subjects

✍ Scribed by Kroetz, Deanna L; Kerr, Bradley M; Mcfarland, Lynne V; Loiseau, Pierre; Wilensky, Alan J; Levy, René H

Book ID
109845251
Publisher
Nature Publishing Group
Year
1993
Tongue
English
Weight
884 KB
Volume
53
Category
Article
ISSN
0009-9236

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## Abstract Microsomal epoxide hydrolase (mEPHX) is a critical metabolic enzyme involved in the activation and subsequent detoxification of specific tobacco carcinogens. __mEPHX__ harbors polymorphisms in exon 3 and exon 4 that modulate enzymatic activity. The exon 3 polymorphism decreases mEPHX me