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Microsomal cholesterol epoxide hydrolase activity in 2-acetylaminofluorene-induced rat liver hyperplastic nodules

✍ Scribed by Ram B. Palakodety; Alfin D. Vaz; Martin J. Griffin


Book ID
115779941
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
406 KB
Volume
36
Category
Article
ISSN
0006-2952

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The carcinogen 2-acetylaminofluorene inh
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Growth arrest in G 1 is a common cellular response to DNA damage. In the present study, liver regeneration was combined with continuous exposure for 2-acetylaminofluorene (AAF) to study mechanisms of carcinogen-induced growth arrest in vivo. Growth arrest of uninitiated hepatocytes is central for AA