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Measurement of Free Intracellular Calcium in the Brain by 19F-Nuclear Magnetic Resonance Spectroscopy

✍ Scribed by H. S. Bachelard; R. S. Badar-Goffer; K. J. Brooks; S. J. Dolin; P. G. Morris

Book ID: 111174870
Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 285 KB
Volume: 51
Category: Article
ISSN: 0022-3042
DOI: 10.1111/j.1471-4159.1988.tb03102.x

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## Abstract __In vivo__ ^19^F NMR measurements of trifluorinated neuroleptics in the rat brain were made using a 13 × 18 mm surface coil at 4.7 T. The signal of fluphenazine was obtained within 8–15 min from brains of living rats treated chronically with drug doses of 5–30 mg/kg. Following the intr