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Measurement of endogenous tryptamine in rat brain by capillary column gas chromatography mass spectrometry

✍ Scribed by Olof Beck; Göran Flodberg


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
289 KB
Volume
11
Category
Article
ISSN
1076-5174

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✦ Synopsis


A capillary column gas chromatographic mass spectrometric method, involving the use of a deuterated analogue as internal standard, was developed and used to identify and quantify tryptamine in the rat brain. The mean level of tryptamine in rat whole brain was 0.54 pmolg-l.


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✍ F. Artigas; C. Suñol; J. M. Tusell; E. Martínez; E. Gelpí 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 255 KB 👁 2 views

The development of an analytical method for the determination of brain tryptamine using capillary gas chromatography mass spectrometry (selected ion monitoring) is presented. The method involves solvent extraction of brain homogenates and further derivatization (pentafluoropropionyl derivatives) of