The development of an analytical method for the determination of brain tryptamine using capillary gas chromatography mass spectrometry (selected ion monitoring) is presented. The method involves solvent extraction of brain homogenates and further derivatization (pentafluoropropionyl derivatives) of
Determination of ligustilide in rat blood and tissues by capillary gas chromatography/mass spectrometry
β Scribed by Yunfeng Shi; Langchong He; Sicen Wang
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 123 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.614
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A capillary column gas chromatographic mass spectrometric method, involving the use of a deuterated analogue as internal standard, was developed and used to identify and quantify tryptamine in the rat brain. The mean level of tryptamine in rat whole brain was 0.54 pmolg-l.
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