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Measurement and Prediction of Oral Absorption

โœ Scribed by Joerg Keldenich


Book ID
102776259
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
609 KB
Volume
6
Category
Article
ISSN
1612-1872

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Computational-Regulatory Developments in
โœ G. Valsami; P. Macheras ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 459 KB

## Abstract Early prediction of human intestinal absorption is important in selection of potential orally administered drugs. Various computational models for prediction of the fraction of dose absorbed, __Fa__, have been developed. In 1989, a sigmoidal relationship between __Fa__ and drug absorpti