Computational-Regulatory Developments in
✍
G. Valsami; P. Macheras
📂
Article
📅
2011
🏛
Wiley (John Wiley & Sons)
🌐
English
⚖ 459 KB
## Abstract Early prediction of human intestinal absorption is important in selection of potential orally administered drugs. Various computational models for prediction of the fraction of dose absorbed, __Fa__, have been developed. In 1989, a sigmoidal relationship between __Fa__ and drug absorpti