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Prediction of drug-drug interaction during oral absorption of carrier-mediated compounds in humans

โœ Scribed by Doo-Man Oh; Gordon L. Amidon


Book ID
112960113
Publisher
Springer
Year
1994
Tongue
English
Weight
600 KB
Volume
17
Category
Article
ISSN
0253-6269

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## Abstract Early prediction of human intestinal absorption is important in selection of potential orally administered drugs. Various computational models for prediction of the fraction of dose absorbed, __Fa__, have been developed. In 1989, a sigmoidal relationship between __Fa__ and drug absorpti