Mean residence time in peripheral tissue
โ Scribed by Patrick J. McNamara; Joseph C. Fleishaker; Thomas L. Hayden
- Book ID
- 112474909
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 640 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1573-8744
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The single pass mean residence time in peripheral tissues, f , , is a characteristic constant of linear pharmacokinetic systems and nonlinear systems with linear distribution kinetics. It is descriptive of distribution kinetics in such systems and is not dependent on elimination kinetics as are othe
The evaluation of mean residence times of drugs and metabolites provides a simple measure of the tendency for such substances to remain in various parts of the body.'-7 Most attention has been given to the evaluation of the mean residence times of the parent drug'-' although it is often of interest