✦ LIBER ✦

Mean residence time in peripheral tissue: A linear disposition parameter useful for evaluating a drug's tissue distribution

✍ Scribed by Peter Veng-Pedersen; William Gillespie

Book ID: 112472626
Publisher: Springer
Year: 1984
Tongue: English
Weight: 364 KB
Volume: 12
Category: Article
ISSN: 1573-8744
DOI: 10.1007/bf01060131

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Single pass mean residence time in perip

Single pass mean residence time in peripheral tissues: A distribution parameter intrinsic to the tissue affinity of a drug

✍ Peter Veng-Pedersen; William R. Gillespie 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 718 KB

The single pass mean residence time in peripheral tissues, f , , is a characteristic constant of linear pharmacokinetic systems and nonlinear systems with linear distribution kinetics. It is descriptive of distribution kinetics in such systems and is not dependent on elimination kinetics as are othe

A method for evaluating the mean residen

A method for evaluating the mean residence times of metabolites in the body, systemic circulation, and the peripheral tissue not requiring separate i.v. administration of metabolite

✍ Peter Veng-Pedersen; William R. Gillespie 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 272 KB 👁 2 views

The evaluation of mean residence times of drugs and metabolites provides a simple measure of the tendency for such substances to remain in various parts of the body.'-7 Most attention has been given to the evaluation of the mean residence times of the parent drug'-' although it is often of interest