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Maxikdiol: a novel dihydroxyisoprimane as an agonist of Maxi-K channels

✍ Scribed by Singh, Sheo B.; Goetz, Michael A.; Zink, Deborah L.; Dombrowski, Anne W.; Polishook, Jon D.; Garcia, Maria L.; Schmalhofer, William; McManus, Owen B.; Kaczorowski, Gregory J.


Book ID
121840819
Publisher
Royal Society of Chemistry
Year
1994
Weight
507 KB
Volume
22
Category
Article
ISSN
1472-7781

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Palladium-catalyzed hydroxycarbonylation
✍ Joseph P. Simeone; Matthew P. Braun; Luping Liu; Swaminathan R. Natarajan πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 148 KB

## Abstract Carbon‐14 labeled sodium formate was utilized for the preparation of a radiolabeled tracer to support the development of a Maxi‐K channel blocker. Key to the process was a palladium‐catalyzed hydroxycarbonylation of a bromoarene for installation of the radiolabel. Copyright Β© 2010 John