Background. A phase III randomized comparison of radiotherapy alone versus combination chemotherapy and concurrent continuous-course radiotherapy was performed at the Cleveland Clinic Foundation. Methods. Between March 1990 and June 1995, 100 patients with resectable stage III and IV squamous cell
Mature results of a Phase III randomized trial comparing concurrent chemoradiotherapy with radiation therapy alone in patients with Stage III and IV squamous cell carcinoma of the head and neck
β Scribed by David J. Adelstein; Pierre Lavertu; Jerrold P. Saxton; Michelle Secic; Benjamin G. Wood; John R. Wanamaker; Isaac Eliachar; Marshall Strome; Marjorie A. Larto
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 102 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
The current study presents mature results from a Phase III randomized trial comparing radiation therapy and concurrent chemoradiotherapy in patients with resectable American Joint Committee on Cancer Stage III and IV disease.
π SIMILAR VOLUMES
Background. Treating the neck after organpreservation treatment with radiotherapy or chemoradiotherapy can be problematic. Methods. To develop management guidelines, we reviewed the results of a 100-patient phase-3 trial that had compared outcome after radiotherapy alone with outcome after chemorad
## BACKGROUND. The authors previously have found that in patients with locally advanced squamous cell carcinoma of the head and neck (SCC-HN), alternating chemoradiotherapy (ALT) was superior to low-total-dose conventional radiotherapy alone. The purpose of this randomized trial was to compare the
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