## Background: Induction chemotherapy in locoregionally advanced squamous cell carcinoma of the head and neck (scchn) might improve survival with respect to radiation therapy alone. furthermore, chemotherapy represents the only therapeutic option in metastatic head and neck carcinoma. ## Methods:
High-dose intra-arterial cisplatin and concurrent hyperfractionated radiation therapy in patients with locally advanced primary squamous cell carcinoma of the head and neck: Report of a phase II study
β Scribed by William F. Regine; Joseph Valentino; William John; Gayle Storey; David Sloan; Daniel Kenady; Pushpa Patel; Calixto Pulmano; Susanne M. Arnold; Mohammed Mohiuddin
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 106 KB
- Volume
- 22
- Category
- Article
- ISSN
- 1043-3074
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initial entry of 34 patients. Cancer Center, University of Miami School of RESULTS. At a median follow-up of 41 months (range, 12-80 months), 44 patients Medicine, Miami, Florida. were alive with a projected median overall survival of 54 months. Grade 3/4 muco-2 Regional Cancer Center, Baptist Hosp
The current study presents mature results from a Phase III randomized trial comparing radiation therapy and concurrent chemoradiotherapy in patients with resectable American Joint Committee on Cancer Stage III and IV disease.
The contents of this article are solely the responsibility of the authors and do not necessarily represent the official views of the National Cancer Institute.