𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hyperfractionated radiation therapy and 5-fluorouracil, cisplatin, and mitomycin-C (± granulocyte-colony stimulating factor) in the treatment of patients with locally advanced head and neck carcinoma

✍ Scribed by André A. Abitbol; Kasi S. Sridhar; Alan A. Lewin; James G. Schwade; William Raub Jr.; Aaron Wolfson; Carlos Gonzalez-Angulo; Anthony Adessa; W. Jarrard Goodwin; Arnold M. Markoe

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
166 KB
Volume
80
Category
Article
ISSN
0008-543X

No coin nor oath required. For personal study only.

✦ Synopsis

initial entry of 34 patients. Cancer Center, University of Miami School of RESULTS. At a median follow-up of 41 months (range, 12-80 months), 44 patients Medicine, Miami, Florida.

were alive with a projected median overall survival of 54 months. Grade 3/4 muco-2 Regional Cancer Center, Baptist Hospital of sitis, observed in 65% of patients, was equally prevalent and prolonged in both G-Miami, Miami, Florida.

CSF-treated (/) and G-CSF-naive (0) patients. Grade 3/4 leukopenia was present in 45% and 36% of G-CSF0 and G-CSF/ patients, respectively. The 3-year locoregi-

📜 SIMILAR VOLUMES

A phase II trial of cisplatin, methotrex
A phase II trial of cisplatin, methotrexate, levofolinic acid, and 5-fluorouracil in the treatment of patients with locally advanced, metastatic squamous cell carcinoma of the head and neck
✍ Francesco Caponigro; Pasquale Comella; Paolo Marcolin; Francesco Russo Spena; Ma 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 89 KB 👁 2 views

## Background: Induction chemotherapy in locoregionally advanced squamous cell carcinoma of the head and neck (scchn) might improve survival with respect to radiation therapy alone. furthermore, chemotherapy represents the only therapeutic option in metastatic head and neck carcinoma. ## Methods:

A phase I clinical and pharmacologic stu
A phase I clinical and pharmacologic study of a carboplatin and irinotecan regimen combined with recombinant human granulocyte-colony stimulating factor in the treatment of patients with advanced nonsmall cell lung carcinoma
✍ Hiroaki Okamoto; Akira Nagatomo; Hideo Kunitoh; Hiroshi Kunikane; Koshiro Watana 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB 👁 2 views

BACKGROUND. This Phase I study was designed to determine the toxicity and efficacy of a carboplatin and irinotecan (CPT-11) regimen with recombinant human granulocyte colony-stimulating factor (rhG-CSF) support for patients with advanced nonsmall cell lung carcinoma. ## METHODS. Treatment consist

Multimodality treatment of 128 patients
Multimodality treatment of 128 patients with locally advanced breast carcinoma in the era of mammography screening using standard polychemotherapy with 5-fluorouracil, epirubicin, and cyclophosphamide : Prognostic and therapeutic implications
✍ Ylva A. Karlsson; Per O. Malmström; Thomas Hatschek; Tommy G. Fornander; Martin 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 212 KB 👁 2 views

## BACKGROUND. Locally advanced breast carcinoma is associated with a poor prognosis. With single treatment modalities, i.e., surgery and/or radiation therapy, results have been consistently dismal. However, several earlier reports have indicated improvement in survival with a combined modality ap