Matrix metalloproteinase3 gene promoter polymorphisms and their haplotypes are associated with gastric cancer risk in eastern Indian population
โ Scribed by Sanjib Dey; Sami Stalin; Arnab Gupta; Debjit Saha; Kousik Kesh; Snehasikta Swarnakar
- Book ID
- 112142352
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 273 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0899-1987
- DOI
- 10.1002/mc.21837
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Peptidyl-prolyl cis/trans isomerase (PPIase), PIN1, has been found to be a critical catalyst that involves in multiple oncogenic signaling pathways. Recently, several putative functional polymorphisms of the PIN1 gene have been identified to be associated with cancer risk. In this study, we tested t
## Communicated by Stephen Chanock Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of MMP genes, which can affect the respective MMP production in an allele-specific manner, have been well characterized.