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Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population

โœ Scribed by Jie Yang; Zhibin Hu; Yaochu Xu; Jin Shen; Juyin Niu; Xu Hu; Jiantao Guo; Qingyi Wei; Xinru Wang; Hongbing Shen

Book ID
116333268
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
113 KB
Volume
215
Category
Article
ISSN
0304-3835

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## Abstract Interleukin 1ฮฒ (ILโ€1ฮฒ) is a multifunctional cytokine that upregulates the inflammatory response, and participates in carcinogenesis, malignant transformation, tumor growth, invasion and metastasis. Two potentially functional polymorphisms (Tโ€31C and Cโ€511T) in the __ILโ€1__ฮฒ gene promote