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Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes

✍ Scribed by Zhou, Y.

Book ID
126450932
Publisher
Oxford University Press
Year
2003
Tongue
English
Weight
92 KB
Volume
25
Category
Article
ISSN
0143-3334

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## Abstract Matrix metalloproteinase‐2 (MMP‐2) and ‐9 (MMP‐9) play an important role in cancer initiation, invasion, and metastasis. The aim of this study was to investigate whether common genetic variants in these two key MMPs are associated with the development and progression of colorectal cance