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Maternal MTHFR mutation and congenital heart defects

✍ Scribed by Jose Hernandez-Robles (F); James C. Huhta; Jenny Leshko


Book ID
113430213
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
78 KB
Volume
193
Category
Article
ISSN
1097-6868

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BACKGROUND: Congenital heart defects (CHDs) are among the most prevalent and serious of birth defects. Multiple maternal factors are thought to contribute to CHD development, including folate intake. Maternal DNA methylation, which is dependent on folate metabolism, may impact the risk of CHDs. Our