Congenital heart defects and maternal derangement of homocysteine metabolism
✍ Scribed by Livia Kapusta; Michèle L.M. Haagmans; Eric A.P. Steegers; Marinus H.M. Cuypers; Henk J. Blom; Tom K.A.B. Eskes
- Book ID
- 117166543
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 23 KB
- Volume
- 135
- Category
- Article
- ISSN
- 1097-6833
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## BACKGROUND: The purpose of this study was to identify metabolic, genetic, and lifestyle factors that discriminate between women who have pregnancies affected by congenital heart defects (CHDs) from those who have unaffected pregnancies. METHODS: We analyzed the concentrations of 13 serum biomar
BACKGROUND: Congenital heart defects (CHDs) are among the most prevalent and serious of birth defects. Multiple maternal factors are thought to contribute to CHD development, including folate intake. Maternal DNA methylation, which is dependent on folate metabolism, may impact the risk of CHDs. Our