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Maternal-fetal pharmacokinetics of zidovudine in rats

✍ Scribed by Christine S.-H. Huang; F. Douglas Boudinot; Stuart Feldman

Book ID
109388515
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
142 KB
Volume
85
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES

Pharmacokinetics and saturable renal tub
Pharmacokinetics and saturable renal tubular secretion of zidovudine in rats
✍ Bela A. Patel; Chung K. Chu; F. Douglas Boudinot πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 671 KB

The purpose of this study was to assess the effects of dose on the pharmacokinetics of zidovudine (3'-azido-3'-deoxythymidine; AZT) in rats. Zidovudine (AZT) was administered intravenously at doses of 10, 50, 100, and 250 mgikg. Plasma and urine AZT concentrations were determined by HPLC. Plasma AZT