Depression of metallothionein in fetal rat liver following maternal cadmium exposure
β Scribed by M.P. Waalkes; J.U. Bell
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 454 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0300-483X
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π SIMILAR VOLUMES
Cadmium (Cd) and zinc (Zn) concentrations were determined by solid sampling atomic absorption spectrometry (AAS) in rat maternal and fetal tissues after exposure to cadmium. Cadmium was administered subcutaneously as CdCl2 in saline daily during pregnancy. Two experiments were performed. In expt. I
Administration of 60 ppm cadmium (Cd) in drinking water from the 1st to the 20th day of gestation to female rats did not affect the viability, body weight gain, food, and water consumption of offspring. The blood hemoglobin level was reduced in 2-week-old females and males but not in 16-week-old off
Metallothionein (MT), induced in different organs in response to heavy metals and oxidative conditions, exerts antioxidant properties and thus could be implicated in cardiovascular physiopathology. The aim of this study was to investigate the capacity of cadmium (Cd) and isoproterenol to induce in v