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Maternal and paternal origin of extra chromosome in trisomy 21

โœ Scribed by Margareta Mikkelsen; Anni Hallberg; Hanne Poulsen


Publisher
Springer
Year
1976
Tongue
English
Weight
325 KB
Volume
32
Category
Article
ISSN
0340-6717

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Of 61 families of children with trisomy 21, polymorphism of chromosome 21 elucidating the origin of the extra chromosome was found in 42. Nondisjunction was of paternal origin in 8 cases (19.04%) and the anomaly occurred with equal frequency during the first and second meiotic divisions. Maternal no

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