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Origin of the extra chromosome No. 21 in Down's syndrome

โœ Scribed by P. Wagenbichler; W. Killian; A. Rett; W. Schnedl


Publisher
Springer
Year
1976
Tongue
English
Weight
329 KB
Volume
32
Category
Article
ISSN
0340-6717

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๐Ÿ“œ SIMILAR VOLUMES


Parental origin of the extra chromosome
โœ R. E. Magenis; K. M. Overton; J. Chamberlin; T. Brady; E. Lovrien ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› Springer ๐ŸŒ English โš– 545 KB

Chromosome 21 fluorescent heteromorphisms were studied in 42 patients with Down's syndrome, their parents and their siblings. Included in this number are two instances of an aunt and niece affected with trisomy 21, and one of affected siblings. One case has a de novo 21/21 translocation. Blood group

Origin of the extra chromosome in trisom
โœ J. F. Mattei; M. G. Mattei; S. Ayme; F. Giraud ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› Springer ๐ŸŒ English โš– 230 KB

Of 61 families of children with trisomy 21, polymorphism of chromosome 21 elucidating the origin of the extra chromosome was found in 42. Nondisjunction was of paternal origin in 8 cases (19.04%) and the anomaly occurred with equal frequency during the first and second meiotic divisions. Maternal no

Parental origin of chromosomes in Down's
โœ Carolina H. Manning; Harold O. Goodman ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Springer ๐ŸŒ English โš– 200 KB

The number of 21 chromosomes of 15 individuals with Down's syndrome and their parents were examined in an attempt to determine the parental origin of the extra number 21 chromosome and the stage of meiosis at which nondisjunction occurred. Chromosomes were stained with quinacrine hydrochloride and p