Mass Spectrometric Quantitation of Chiral Drugs by the Kinetic Method
β Scribed by Tao, W. Andy; Gozzo, Fabio C.; Cooks, R. Graham
- Book ID
- 126277990
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 84 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0003-2700
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## Abstract A novel mass spectrometric method is applied to rapid, accurate, quantitative analysis of chiral phenylglycine. Transitionβmetalβbound complex ions containing the chiral phenylglycine are generated by electrospray ionization mass spectrometry and subjected to collisionβinduced dissociat
## Abstract Chiral analysis is an important task of analytical chemistry. Besides separation techniques, mass spectrometry can be applied in this field. One mass spectrometric approach is based on Cooks' kinetic method. The method was successfully applied in a static system in which the concentrati