The optimal feed rate profiles of glucose and ammonium hydroxide were calculated using a proposed model, and implemented for the production of poly-hydroxybutyric acid (PHB) by Alcaligenes eutrophus. By implementing these optimal feed rates with a high glucose feed concentration of 700 g/L and an a
✦ LIBER ✦
Mass production of poly-β-hydroxybutyric acid by fully automatic fed-batch culture of methylotroph
✍ Scribed by Takahiro Suzuki; Tsuneo Yamane; Shoichi Shimizu
- Publisher
- Springer
- Year
- 1986
- Tongue
- English
- Weight
- 742 KB
- Volume
- 23
- Category
- Article
- ISSN
- 1432-0614
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## Abstract The production of β‐galactosidase by __Kluyveromyces fragilis__ was studied in different culture systems, with dissolved oxygen concentration control and using defined media. An operating strategy of fed‐batch culture with automatic control of substrate addition regulated by dissolved o