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Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer

✍ Scribed by Ghassan El Maalouf; Christophe Le Tourneau; Georges Nicolas Batty; Sandrine Faivre; Eric Raymond


Book ID
116395362
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
235 KB
Volume
35
Category
Article
ISSN
0305-7372

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## Abstract Degradation of extracellular matrix is crucial for malignant tumour growth, invasion, metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc‐dependent neutral endopeptidases collectively capable of degrading essentially all matrix components. Elevated levels