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Targeting cancer-associated fibroblasts through inhibition of protein synthesis to abrogate resistance to chemotherapies in pancreatic cancer

✍ Scribed by Duluc, Camille; Moatassim-Billah, Siham; Chalabi, Mounira; Martineau, Yvan; Garmy-Susini, Barbara; Breibach, Florence; Delisle, Marie-Bernadette; Guillermet-Guibert, Julie; Schmid, Herbert; Pyronnet, Stéphane; Bousquet, Corinne

Book ID
127237117
Publisher
S. Karger AG
Year
2014
Tongue
English
Weight
51 KB
Volume
14
Category
Article
ISSN
1424-3903

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## Abstract Pancreatic cancer is one of the most aggressive human tumors with a 5‐year survival rate of only 3% and a striking resistance to chemotherapy and radiotherapy. The search for new therapeutic approaches includes strategies exploiting the deregulation of apoptotic pathways commonly found