Comparative genomic hybridization (CGH) was used in a retrospective analysis of chromosomal imbalances in frozen primary tumor specimens from 14 endometrial carcinoma patients. Chromosome changes were detected in nine cases (64%), and tumor stage and grade tended to parallel the degree of genomic im
Mapping of multiple DNA gains and losses in primary small cell lung carcinomas by comparative genomic hybridization
- Book ID
- 123251317
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 144 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0169-5002
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Comparative genomic hybridization (CGH) was used to detect and map the regions of gain, high-level amplification, and loss of DNA sequences in 14 liposarcomas. Thirteen tumors showed DNA sequence copy number changes of one or more genomic regions (mean, six aberrationdtumor; range, 0-1 7). These abe