Comparative genomic hybridization (CGH) was used to detect and map the regions of gain, high-level amplification, and loss of DNA sequences in 14 liposarcomas. Thirteen tumors showed DNA sequence copy number changes of one or more genomic regions (mean, six aberrationdtumor; range, 0-1 7). These abe
Gains and losses of DNA sequences in malignant mesothelioma by comparative genomic hybridization
✍ Scribed by Paula Kivipensas; Anna-Maria Björkqvist; Ritva Karhu; Katarina Pelin; Kaija Linnainmaa; Lauri Tammilehto; Karin Mattson; Olli-Pekka Kallioniemi; Sakari Knuutila
- Book ID
- 113253743
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 520 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0165-4608
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Comparative genomic hybridization (CGH) makes it possible to detect losses and gains of DNA sequences along all chromosomes in a tumor specimen based on the hybridization of differentially labeled tumor and normal DNA to normal human metaphase chromosomes. In this study, CGH analysis wa
Comparative genomic hybridization (CGH) was used in a retrospective analysis of chromosomal imbalances in frozen primary tumor specimens from 14 endometrial carcinoma patients. Chromosome changes were detected in nine cases (64%), and tumor stage and grade tended to parallel the degree of genomic im