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Mapping of a DNA-bidding domain of simian virus 40 T-antigen using non-defective adenovirus 2—simian virus 40 hybrid viruses

✍ Scribed by Mathias Montenarh; Wolfgang Deppert; Roland Henning


Book ID
115913178
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
425 KB
Volume
142
Category
Article
ISSN
0014-5793

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Structure-based design of a disulfide-li
✍ Meinke, Gretchen ;Phelan, Paul ;Fradet-Turcotte, Amélie ;Archambault, Jacques ;B 📂 Article 📅 2011 🏛 International Union of Crystallography 🌐 English ⚖ 789 KB

With the aim of forming the ‘lock-washer’ conformation of the origin-binding domain of SV40 large T antigen in solution, using structure-based analysis an intermolecular disulfide bridge was engineered into the origin-binding domain to generate higher order oligomers in solution. The 1.7 Å resolutio