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Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations

✍ Scribed by Anna St. Swierzko; Maciej Cedzynski; Iwona Domzalska-Popadiuk; Shirley L. MacDonald; Monika Borkowska-Klos; Anne P.M. Atkinson; Agnieszka Szala; Aleksandra Jopek; Jens C. Jensenius; Masaya Kawakami; Jerzy Szczapa; Misao Matsushita; Janusz Szemraj; Marc L. Turner; David C. Kilpatrick


Book ID
116757288
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
422 KB
Volume
46
Category
Article
ISSN
0161-5890

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## Abstract The lectin pathway of the complement system is activated when Mannan‐binding lectin (MBL) in complex with MASP‐2 binds microorganisms. Polymorphisms in both genes are responsible for low serum levels, which associate with increased risk of infection and autoimmune disease. The present s