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Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cells

✍ Scribed by Venkataraman, Sujatha; Jiang, Xiaohong; Weydert, Christine; Zhang, Yuping; Zhang, Hannah J; Goswami, Prabhat C; Ritchie, Justine M; Oberley, Larry W; Buettner, Garry R

Book ID
110069207
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
360 KB
Volume
24
Category
Article
ISSN
0950-9232

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NIH/3T3 mouse fibroblasts were transfected with the cDNA for manganese superoxide dismutase (MnSOD), and two clones overexpressing MnSOD activity were subsequently characterized by comparison with parental and control plasmidtransfected cells. One clone with a 1.8-fold increase in MnSOD activity had